Experimental and Clinical Research Center (ECRC)
As a joint institution of the Charité – Universitätsmedizin Berlin and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, the Experimental and Clinical Research Center (ECRC) provides the scientific and technical infrastructure, expertise and resources for translational research, including clinical trials, according to competitive criteria. The ECRC provides access to highly advanced technologies, such as ultra high field magnetic resonance imaging, and has a cleanroom laboratory for the production of immunotherapeutic vaccines and a unique infrastructure for patient-centered research in the form of a clinical pharmacology unit in accordance with the American “clinical research center” model. Studies with outpatients can be carried out in specialized university outpatient clinics. If a clinical trial requires hospitalization of the trial participant for several days, this can be provided in the inpatient hospital sites of the Charité.
The aim is to transform findings from basic research into clinical practice to improve the diagnosis, prevention and treatment of the most prevalent diseases in our society (cardiovascular and metabolic diseases, cancer, neurological disorders). An important aspect of the ECRC strategy is to facilitate extensive collaboration and communication between basic scientists and clinical researchers, thus creating a common platform as the basis for successful cooperation.
A research group at the MDC has discovered a protein that protects mature B lymphocytes from stress-induced cell death. It also helps immune cells produce effective antibodies, which can stop the path...more ...
Osmotic stress identified as stimulator of cellular waste disposal
Researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) in Berlin have now discovered a previously unknown mechanism: osmotic stress, i.e. a change in water and ionic balanc...more ...
Jan Philipp Junker receives Helmholtz AI grant
MDC researcher Jan Philipp Junker and his collaborator Maria Colomé-Tatché at Helmholtz Center Munich have received a €200,000 grant to improve big data processing to better understand how gene netw...more ...