Research tradition

The scientists Cécile und Oskar Vogt, between them N. W. Timoféeff-Ressovsky

The scientists Cécile und Oskar Vogt, between them N. W. Timoféeff-Ressovsky

Medical-biological research has a 75-year tradition at Berlin-Buch. Here in 1930 the Institute for Brain Research of the Kaiser Wilhelm Association with the affiliated neurological clinic was established, with Oskar Vogt as director. At that time the institute was the largest and most modern of its kind in the world. Vogt's work focused on histological-anatomic and functional layer- and field structures (topistic) of the cerebral cortex. From 1937 on, Vogt's successor directed the institute's research onto various neuropathological problems including brain tumors. The institute achieved special renown through the work of the Russian geneticist  N. W. Timoféeff-Ressovsky  on gene mutations and the structure of the gene, in part together with Max Delbrück.

At Work: the geneticist Timoféeff-Ressovsky

At Work: the geneticist Timoféeff-Ressovsky

In 1947 the institute and clinic were combined as the Institute for Medicine and Biology and placed under the auspices of the German Academy of Sciences in Berlin. The institute became a well-known center for cancer research with research projects on the chemical genesis of cancer, oncogenic viruses, biochemistry, immunology, genetics and radiobiology as well as the clinical treatment of tumors. From 1956 onward, a second emphasis was placed on cardiovascular research, likewise integrating research and clinical practice. In 1972 the different Academy research institutes at Buch merged to form the central institutes for molecular biology, for cancer research and for cardiovascular research.

The former Robert Rössle Hospital, the so-called Tumor Clinic

The former Robert Rössle Hospital, the so-called Tumor Clinic 

With the unification of West and East Germany in 1990, the academy institutes were phased out in accordance with the unification agreement. Subsequently, the  Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch was founded on the Campus in 1992. Starting in 1995, biotechnology companies have settled on the Campus in the Innovation and Founding Center. In 2000 the Leibniz Institute for Molecular Pharmacology (FMP) was established.

Since 2011 the Experimental and Clinical Research Center (ECRC) has been housed in the Robert Rössle Building of the former Tumor Clinic. The ECRC is a joint institution of the Berlin Charité and the Max Delbrück Center with research departments and outpatient clinics of different medical departments.

Building of the Institute for Brain Research of the Kaiser Wilhelm Society, now named after the founders Cécile and Oskar Vogt

Building of the Institute for Brain Research of the Kaiser Wilhelm Society, now named after the founders Cécile and Oskar Vogt

News Buch Berlin

Equality in research drives innovation

Marking International Women's Day, Federal Research Minister Dorothee Bär met with female researchers at the Max Delbrück Center

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T-knife Therapeutics Announces Authorization of Clinical Trial Application for TK-6302, A Multi-Armored, CRISPR based T cell Therapy for Solid Tumors

Phase 1 ATLAS trial to evaluate TK-6302 in patients with advanced PRAME-positive solid tumors authorized for initiation

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Gut microbes affect the heart via the brain

Researchers at the Max Delbrück Center have uncovered how a bacterial metabolite produced in the gut regulates heart function through specific brain cells. The findings, published in “Circulation Rese...

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Events Buch Berlin

13.03.2026, 16:00
Silent Disco im Bürgerhaus

für Jung und Alt

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17.03.2026, 18:00
Campus-Kino: "Greenpeace - wie alles begann"

Der Freundeskreis des Max Delbrück Center lädt herzlich ein!

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18.03.2026, 08:30
vocatium Berlin focus 2026: Fachmesse für Ausbildung+Studium

Entdecke berufliche Möglichkeiten, informiere dich und sprich mit Expert:innen über Einstieg, Voraussetzungen und Bewerbung.

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